Líneas de investigación actuales.
  • Desarrollo de fármacos para prevenir los efectos adversos del envejecimiento (geroprotectores), mediante un enfoque de farmacología de redes.
  • Impacto de los factores ambientales en el envejecimiento y la edad epigenética.
Proyectos de investigación vigentes.
  • Búsqueda y reposicionamiento computacional de moléculas activas con potencial como geroprotectores.
  • Comprendiendo las desigualdades sociales y de marginalidad en salud en adultos mayores a través de un análisis de epigenética social en una cohorte de la Ciudad de México.
Producción científica de los últimos 5 años.
  1. Barrera-Vázquez, O. S., Magos-Guerrero, G. A., Escobar-Ramírez, J. L., & Gomez-Verjan, J. C. (2023). Natural Products as a Major Source of Candidates for Potential SenolyticCompounds obtained by in silico Screening. Medicinal Chemistry, 19(7), 653-668. https://doi.org/10.2174/1573406419666221019153537
  2. Castillejos-López, M., Romero, Y., Varela-Ordoñez, A., Flores-Soto, E., Romero-Martinez, B. S., Velázquez-Cruz, R., Vázquez-Pérez, J. A., Ruiz, V., Gomez-Verjan, J. C., Rivero-Segura, N. A., Camarena, Á., Torres-Soria, A. K., Gonzalez-Avila, G., Sommer, B., Solís-Chagoyán, H., Jaimez, R., Torres-Espíndola, L. M., & Aquino-Gálvez, A. (2023). Hypoxia Induces Alterations in the Circadian Rhythm in Patients with Chronic Respiratory Diseases. Cells, 12(23), 2724. https://doi.org/10.3390/cells12232724
  3. Gomez-Verjan, J. C., Zepeda-Arzate, E. A., Santiago-de-la-Cruz, J. A., Estrella-Parra, E. A., & Rivero-Segura, N. A. (2023). Unraveling the Neuroprotective Effect of Natural Bioactive Compounds Involved in the Modulation of Ischemic Stroke by Network Pharmacology. Pharmaceuticals, 16(10), 1376. https://doi.org/10.3390/ph16101376
  4. Romero-Martínez, B. S., Sommer, B., Solís-Chagoyán, H., Calixto, E., Aquino-Gálvez, A., Jaimez, R., Gomez-Verjan, J. C., González-Avila, G., Flores-Soto, E., & Montaño, L. M. (2023). Estrogenic Modulation of Ionic Channels, Pumps and Exchangers in Airway Smooth Muscle. International Journal of Molecular Sciences, 24(9), 7879. https://doi.org/10.3390/ijms24097879
  5. Barrera-Vazquez O, Santiago-de-la-Cruz JA, Rivero-Segura NA, Estrella-Parra EA, Morales-Paoli GS, Flores-Soto E, Gomez-Verjan JC. (2023). Data-Driven Approaches Used for Compound Library Design for the Treatment of Parkinson’s Disease. International Journal of Molecular Sciences. 24(2):1134.
  6. Pedraza-Vázquez G, Mena-Montes B, Hernández-Álvarez D, Gómez-Verjan JC, Toledo-Pérez R, López-Teros MT, Königsberg M, Gómez-Quiroz LE, Luna-López A. (2023). A low-intensity lifelong exercise routine changes miRNA expression in aging and prevents osteosarcopenic obesity by modulating inflammation. Arch Gerontol Geriatr. 105:104856.
  7. Barrera-Vázquez OS, Gomez-Verjan JC, Ramírez-Aldana R, Torre PG-d, Rivero-Segura NA. (2022). Structural and Pharmacological Network Analysis of miRNAs Involved in Acute Ischemic Stroke: A Systematic Review. International Journal of Molecular Sciences. 23(9):4663.
  8. Montaño LM, Sommer B, Gomez-Verjan JC, Morales-Paoli GS, Ramírez-Salinas GL, Solís-Chagoyán H, Sanchez-Florentino ZA, Calixto E, Pérez-Figueroa GE, Carter R, Jaimez-Melgoza R, Romero-Martínez BS, Flores-Soto E. (2022). Theophylline: Old Drug in a New Light, Application in COVID-19 through Computational Studies. Int J Mol Sci. 9;23(8):4167.
  9. Ramírez-Aldana R, Gomez-Verjan JC, Bello-Chavolla OY, Naranjo L. (2022). A Spatio-temporal study of state-wide case-fatality risks during the first wave of the COVID-19 pandemic in Mexico. Geospat Health. 24;17(s1). doi: 10.4081/gh.2022.1054.
  10. Arroyo P, Esparza-Aguilar M, Martín-Martín V, Gomez-Verjan JC, Parra-Rodríguez L, Cadena-Trejo C, Salazar-Pérez C, Gutiérrez-Robledo LM. (2022). Physical capability in a rural birth cohort at the age of 52: association with early environmental, nutritional, and developmental factors. BMC Geriatr. DOI. 10;22(1):113.
  11. Montaño LM, Sommer B, Solís-Chagoyán H, Romero-Martínez BS, Aquino-Gálvez A, Gomez-Verjan JC, Calixto E, González-Avila G, Flores-Soto E. (2022). Could Lower Testosterone in Older Men Explain Higher COVID-19 Morbidity and Mortalities? Int J Mol Sci.
  12. Principles of Clinical Transcriptomics and Splicing. Gomez-Verjan J.C., Yustis-Rubio J.C., Sulvaran-Guel E. (2022) Principles of Genetics and Molecular Epidemiology. Springer. 1st Edition. Chapter 5. pp 55-65.
  13. Digital Health and Physiomics. Barrera-Vázquez O.S., Rivero-Segura N.A., Gomez-Verjan J.C. (2022) Principles of Genetics and Molecular Epidemiology. Springer, 1st Edition Chapter 10. pp 111-116.
  14. Principles of Network Models and Systems Epidemiology. Ramírez-Aldana R., Hahn-Herrera O., Quiroz-Baez R., Gomez-Verjan J.C. (2022) Principles of Genetics and Molecular Epidemiology. Springer, 1st Edition. Chapter 14  pp. 159-168.
  15. Molecular Pharmacological Tools Applied to Epidemiology. Barrera-Vázquez O.S., Flores-Soto E., Gomez-Verjan J.C. (2022) Principles of Genetics and Molecular Epidemiology. Springer, 1st Edition Chapter 15. pp 169-180.
  16. Systems Medicine Applied to Epidemiology. Yustis-Rubio J.C., Gomez-Verjan J.C. (2022) Principles of Genetics and Molecular Epidemiology. Springer,1st Edition. Chapter 16. pp. 181-187.
  17. Genomic Surveillance in Public Health. Barrera-Vázquez O.S., Sulvaran-Guel E., Pedraza-Vázquez G., Gomez-Verjan J.C. (2022)  Principles of Genetics and Molecular Epidemiology. Springer, 1st Edition. Chapter 17. pp. 189-201.
  18. Ramírez-Aldana R, Gomez-Verjan JC, Bello-Chavolla OY, García-Peña C. (2021). Spatial epidemiological study of the distribution, clustering, and risk factors associated with early COVID-19 mortality in Mexico. PLoS One.  21;16(7):e0254884. doi: 10.1371/journal.pone.0254884.
  19. Editores: Gomez-Verjan JC y Rivero-Segura NA. (2022). Principles of Genetics and Molecular Epidemiology. (Principios de Epidemiología Molecular y Genética). Springer-Nature. 1sr Edition. ISBN: 978-3-030-89601-0
  20. Gomez-Verjan JC, Esparza-Aguilar M, Martín-Martín V, Salazar-Perez C, Cadena-Trejo C, Gutierrez-Robledo LM, Martínez-Magaña JJ, Nicolini H, Arroyo P. (2021). Years of Schooling Could Reduce Epigenetic Aging: A Study of a Mexican Cohort. Genes (Basel). 13;12(9):1408.
  21. Barrera-Vázquez OS, Gómez-Verjan JC, Magos-Guerrero GA. (2021). Chemoinformatic Screening for the Selection of Potential Senolytic Compounds from Natural Products. Biomolecules. 22;11(3):467.
  22. Rivero-Segura NA, Gomez-Verjan JC. (2021). In Silico Screening of Natural Products Isolated from Mexican Herbal Medicines against COVID-19. Biomolecules. 4;11(2):216.
  23. Spatial analysis of COVID-19 spread in Iran: Insights into geographical and structural transmission determinants at a province level. (2020). Ramírez-Aldana R, Gomez-Verjan JC, Bello-Chavolla OY. PLoS Negl Trop Dis.
  24. Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective. Rivero-Segura NA, Bello-Chavolla OY, Barrera-Vázquez OS, Gutierrez-Robledo LM, Gomez-Verjan JC. (2020). Ageing Res Rev. Vol. 64
  25. Esparza-Aguilar M, Arroyo P, Gómez-Verján JC, Martín-Martín V. (2020). Early life exposure and its association with diseases in adulthood: review of longitudinal studies. Bol Med Hosp Infant Mex. 77(4):153-165.
  26. Gomez-Verjan JC, Barrera-Vázquez OS, García-Velázquez L, Samper-Ternent R, Arroyo P. (2020). Epigenetic variations due to nutritional status in early-life and its later impact on aging and disease. Clin Genet. Apr 4.
  27. Barrera-Vázquez OS, Gomez-Verjan JC. (2020). The Unexplored World of Human Virome, Mycobiome, and Archaeome in Aging. J Gerontol A Biol Sci Med Sci. Sep 25;75(10):1834-1837.
  28. J.C. Yustis-Rubio, J.C. Gomez-Verjan. (2020). Alternative splicing and aging. Clinical Genetics and Genomics of Aging. Springer. 1st Edition. Chapter 7. Pages 125-139. 
  29. OS Barrera-Vázquez, J.C. Gomez-Verjan. (2020) Pharmacological Treatment for Aging: Are We There? Clinical Genetics and Genomics of Aging. Springer. 1st Edition. Chapter 12. Pages 231-245.
  30. Editores: Gomez-Verjan And Rivero-Segura. Springer-Nature. (2020). Clinical Genetics and Genomics of Aging. (Genética Clínica y Genómica del Envejecimiento) 1st Edition. 2020. ISBN: 978-3-030-40955-5
  31. García-Peña C, Ramírez-Aldana R, Parra-Rodriguez L, Gomez-Verjan JC, Pérez-Zepeda MU, Gutiérrez-Robledo LM. (2019). Network analysis of frailty and aging: Empirical data from the Mexican Health and Aging Study.  Exp Gerontol.
  32. Gomez-Verjan JC, Ramírez-Aldana R, Pérez-Zepeda MU, Quiroz-Baez R, Luna-López A, Gutierrez Robledo LM. (2019). Systems biology and network pharmacology of frailty reveal novel epigenetic targets and mechanisms. Sci Rep. 9(1):10593.
  33. Sepúlveda-Robles O, Espinoza-Gutiérrez B, Gomez-Verjan JC, Guzmán-Gutiérrez SL, De Ita M, Silva-Miranda M, Espitia-Pinzón CI, Fernández-Ramírez F, Herrera-Salazar A, Mata-Rocha M, Ortega-Hernández A, Reyes-Chilpa R. (2019). Trypanocidal and toxicological assessment in vitro and in silico of three sesquiterpene lactones from Asteraceae plant species. Food Chem Toxicol. Mar;125:55-61.
  34. Gómez-Verjan JC, Rivero-Segura NA, Estrella-Parra E, Rincón-Heredia R, Madariaga-Mazón A, Flores-Soto E, González-Meljem M, Cerbón M, Reyes-Chilpa R. (2019). Network Pharmacology Uncovers Anticancer Activity of Mammea-Type Coumarins from Calophyllum brasiliense. Planta Med. Jan;85(1):14-23.
Perfil de ResearchGate y número de ORCID.